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HIV (Human Immunodeficiency Virus) weakens the immune system by attacking CD4 cells, which play a key role in protecting the body from infections. Without treatment, HIV can progress to AIDS, a stage where the immune system becomes severely compromised.
With modern antiretroviral therapy (ART), people living with HIV can lead long, healthy lives. ART suppresses the virus, protects the immune system, and significantly reduces the risk of transmission.
The recommended first-line ART regimen for most adults in South Africa is TLD, a fixed-dose combination containing: Tenofovir (TDF), Lamivudine (3TC), Dolutegravir (DTG).
The antiretroviral (ARV) TLD is taken once daily, is highly effective, has a strong safety profile, and is easy to adhere to.
HIV treatment still requires routine monitoring even when you are well-controlled. Patients on TLD should undergo blood tests every 12 months. Annual monitoring ensures continued viral suppression and early detection of potential side effects.
Potential side effects of TLD:
Common side effects (often mild and improve within the first few weeks of treatment):
- Headache
- Nausea or stomach discomfort
- Trouble sleeping or vivid dreams
- Dizziness or tiredness
Less common side effects:
- Mood changes
Rare but serious side effects (these are uncommon, but important to be aware of):
- Kidney problems – This is why kidney tests are recommended yearly.
- Lactic acidosis – A very rare but serious condition where lactic acid builds up in the body. Symptoms may include rapid breathing, abdominal pain, nausea, or muscle pain. Seek urgent care if this occurs.
- Liver problems – Watch for yellowing of the eyes or skin, dark urine, or severe abdominal pain.
- Neural tube defects (pregnancy) – Dolutegravir has a very small increased risk of neural tube defects if taken during early pregnancy. Modern data shows the risk is low, but contraception is strongly recommended for women who can become pregnant.
When to seek medical help:
Contact a healthcare provider immediately if you experience:
- Severe abdominal pain
- Jaundice (yellow eyes/skin)
- Extreme fatigue with muscle pain
- Shortness of breath
- New rash with fever
- Persistent vomiting
- Signs of kidney issues (swelling, decreased urination)
The vast majority of patients on TLD:
- Have excellent viral suppression
- Experience minimal side effects
- Maintain normal kidney and liver function
- Feel healthier and stronger over time
Maintaining long-term health
With consistent adherence to ART and regular health monitoring, HIV becomes a manageable chronic condition. Online Doctor SA supports stable patients by making repeat prescriptions accessible, efficient, and secure.
Online Doctor SA offers a convenient and secure way for healthy patients to renew their HIV prescriptions. Eligible patients can receive a 6-month chronic prescription within 24 hours.
To begin your HIV prescription renewal, visit:
Frequently Asked Questions
What is TLD?
TLD is the recommended first-line HIV treatment in South Africa. It is a once-daily combination of Tenofovir (TDF), Lamivudine (3TC), and Dolutegravir (DTG). It is highly effective, well tolerated, and helps maintain long-term viral suppression.
Can Online Doctor SA help all patients with HIV on ARVs?
The telemedicine service is only suitable for:
– Patients on the standard TLD regimen
– Individuals who have been on HIV treatment for at least one year
– Patients who are stable, well-controlled, and without new symptoms
– Those needing a straightforward renewal of their chronic ARV prescription
Which patients on HIV treatment can Online Doctor SA not help with?
– Newly diagnosed patients
– Patients on second-line, alternate, or complex ARV regimens
– Individuals experiencing new symptoms or treatment concerns
– Patients who are not stable on their current ART
These patients should attend their nearest clinic or healthcare facility for a full in-person assessment.
Do I still need blood tests if I feel fine?
Yes. Annual monitoring is essential even when you feel well. Blood tests check kidney function, viral load, and overall safety of your treatment.
Is medication included in the consultation fee?
No. Your consultation fee covers the online assessment and prescription only. You will use the script to purchase your medication at your preferred pharmacy.
Can I switch to TLD if I am on another regimen?
Switching regimens requires an in-person consultation and monitoring. If you are on a second-line or non-TLD regimen, you should visit your local clinic for guidance.
Can I get a 6 month prescription of ARVs?
Yes you can receive a 6 month chronic prescription for HIV treatment through Online Doctor SA.
How do I start the online consultation?
– Visit www.onlinedoctorsa.co.za
– Complete the HIV clinical form, and await consultation with an online doctor.
– Receive your prescription directly to your email.
– Use your prescription to purchase your medication at any pharmacy in South Africa
Can I get HIV treatment online in South Africa?
With Online Doctor SA, you can receive chronic 6 month prescriptions for your ARVs (HIV treatment), easily and affordably. Simply visit www.onlinedoctorsa.co.za to begin your consultation.
